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Semaglutide

RxCUI 199130

GLP-1 receptor agonist

peptide

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that increases insulin secretion, decreases glucagon secretion, and slows gastric emptying.

Used to improve glycemic control in adults with type 2 diabetes mellitus; also indicated for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity.

Tirzepatide

RxCUI 261551

GIP/GLP-1 receptor agonist

peptide

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist that improves glycemic control and supports weight loss.

Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes; and for chronic weight management in adults with obesity or overweight with weight-related comorbidities.